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Last Updated: Aug 16, 2026
No. of Questions: 175 Questions & Answers with Testing Engine
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| Section | Objectives |
|---|---|
| Topic 1: Part II: Applied Clinical Decision Making | - Case-based pharmacotherapy scenarios
|
| Topic 2: Disease State Management | - Endocrine and metabolic disorders
|
| Topic 3: Part I: Knowledge-Based Assessment | - Foundational pharmacotherapy knowledge
|
| Topic 4: Special Populations | - Renal and hepatic impairment
|
| Topic 5: Patient Care and Pharmacotherapy Principles | - Medication management
|
1. A 13-year-old boy who has asthma, weight 32kg, height 150cm, takes inhaled salmeterol one puff twice daily and inhaled fluticasone 2 puffs twice daily. The patient must stop participation in physical education classes after a few minutes due to shortness of breath. To allow the patient to participate longer, the most effective measure would be to add which of the following?
A) Inhaled cromolyn 30-60 minutes prior to class
B) Inhaled albuterol 15 minutes before class
C) An extra dose of inhaled salmeterol 30-60 minutes before class
D) An extra dose of inhaled fluticasone 1-2 hours before class
2. A patient is started on ledipasvir-sofosbuvir. What would be the best indicator of treatment response?
A) ALT less than three times the upper limit of normal
B) Absence of alpha-fetoprotein
C) HCV RNA below the lower limit of quantification
D) Absence of cryoglobulinemia
3. A 50-year-old patient presents to the physician complaining of anxiety, insomnia, a depressed mood, and decreased energy level. Paroxetine therapy is initiated. Which symptom will be the last to respond?
A) Anxiety
B) Depressed mood
C) Insomnia
D) Decreased energy
4. A 65-year-old man presents to the internal medicine clinic with decreased exercise tolerance, lower extremity edema, and shortness of breath.
He has a history of diastolic dysfunction (ejection fraction of 60%) and hypertension; BP =
150/90 mm Hg, HR = 86 bpm.
Current medications include digoxin 125 mcg daily, furosemide 40 mg daily, enalapril 10 mg twice daily, aspirin 325 mg daily, and potassium 10 mEq twice daily. The digoxin concentration is 0.4 ng/mL.
After resolution of this exacerbation, which of the following should the pharmacotherapy specialist recommend to the internist regarding this patient's maintenance drug therapy?
A) Discontinue digoxin and add amlodipine.
B) Increase digoxin.
C) Increase furosemide.
D) Discontinue digoxin and add metoprolol.
5. A patient is admitted to the hospital after a motor vehicle collision. The patient takes methadone
40 mg once daily for management of an opiate addiction. The remainder of the patient's medical history is unremarkable. The medical resident caring for the patient wants to order methadone but Expresses concern related to the Substance Abuse and Mental Health Services Administration (SAMHSA) regulations.
What is the appropriate action?
A) Order morphine at equivalent dose as an alternative management.
B) Order methadone 40 mg once daily if the medical resident is a registered opioid treatment program (OTP) practitioner.
C) Order methadone 40 mg once daily if the patient shows signs of withdrawal.
D) Order methadone 40 mg once daily during inpatient treatment.
Solutions:
| Question # 1 Answer: B | Question # 2 Answer: C | Question # 3 Answer: C | Question # 4 Answer: D | Question # 5 Answer: D |
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